Successful sequential liver-kidney transplantation in a patient with performed lymphocytotoxic antibodies.

SENSITI ZA TION of potential transplant recipients by formation of Iymphocytotoxic antibodies can be a result of prior blood transfusions, pregnancy. or failed allograft transplantation. While the presence of preformed anti-HlA-A and -B Iymphocytotoxic antibodies does not appear to influence the survival of liver allografts; this has been a contraindication in renal transplantation because of the high incidence of hyperacute rejection.' We report a case of successful transplantation of a renal allograft. in the face of a positive warm T cell crossmatch sequentially following a prior hepatic allograft transplantation from the same donor.